Article
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
BMC medical genetics - 8 Feb 2013
Pechlivanis Sonali, Mühleisen Thomas W, Möhlenkamp Stefan, Schadendorf Dirk, Erbel Raimund, Jöckel Karl-Heinz, Hoffmann Per, Nöthen Markus M, Scherag André, Moebus Susanne
Abstract excerpt
BACKGROUND: Atherosclerosis is the primary cause of coronary heart disease (CHD), preceding the onset of cardiovascular disease by decades in most cases. Here we examine the association between single nucleotide polymorphisms (SNPs) integrated on Metabochip and coronary artery calcification (CAC), a valid risk factor for CHD, in an unselected, population-based German cohort. METHODS: The Metabochip is a custom...
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