Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-ancestry colocalization approaches.

PLoS genetics - 1 Jul 2026

Shen Cathy, Dupuis Josée, Zhang Qihuang

Abstract excerpt

Genome-wide association studies (GWAS) have identified thousands of variants associated with complex traits, but many are non-causal. Statistical fine-mapping methods aim to pinpoint the most likely causal variants among the many associated ones. While most fine-mapping methods were originally limited to single ancestry analysis, multi-ancestry fine-mapping methods are now available, leveraging differences in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Polymorphism, Single Nucleotide
Share to Quantitative Trait Loci
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Source

Open in PubMed Open full text

Identifiers

PMID: 42479736
DOI: 10.1371/journal.pgen.1012221
PMCID: PMC13387578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-ancestry colocalization approaches.PMID 42479736Read ↗

Ultra-fast genetic colocalisation across millions of association signals.Semantic proximity Read ↗

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits.Semantic proximity Read ↗

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traitsSemantic proximity Read ↗

Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations.Semantic proximity Read ↗

Probabilistic Colocalization of Genetic Variants from Complex and Molecular Traits: Promise and LimitationsSemantic proximity Read ↗

COLOCdb: a comprehensive resource for multi-model colocalization of complex traits.Semantic proximity Read ↗

Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx.Semantic proximity Read ↗

SharePro: an accurate and efficient genetic colocalization method accounting for multiple causal signals.Semantic proximity Read ↗

Estimating colocalization probability from limited summary statistics.Semantic proximity Read ↗

A more accurate method for colocalisation analysis allowing for multiple causal variants.Semantic proximity Read ↗

MESuSiE enables scalable and powerful multi-ancestry fine-mapping of causal variants in genome-wide association studies.Semantic proximity Read ↗

MultiSuSiE improves multi-ancestry fine-mapping in All of Us whole-genome sequencing data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.