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Article

Loss of Twist impairs tentacle development and induces epithelial neoplasia in the sea anemone Nematostella vectensis.

Development (Cambridge, England) - 1 Sept 2026

Murguia Patricio Ferrer, Hagauer Julia, Haillot Emmanuel, Ikmi Aissam, Montenegro Juan D, Cole Alison G, Technau Ulrich

Abstract excerpt

Appendages are key features of the body plans of arthropods and vertebrates, yet little is known about appendage formation outside of bilaterians. Here, we investigate the molecular regulation underlying the formation of tentacles, the appendages in cnidarians. We find that the bHLH transcription factor Twist plays a crucial role in tentacle morphogenesis and tissue homeostasis in the sea anemone Nematostella...

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Identifiers

PMID: 42478180
DOI: 10.1242/dev.205340
PMCID: PMC13539428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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