Clonal haematopoiesis of indeterminate potential and epigenetic age acceleration: Systematic review and meta-analysis.

doi:10.1016/j.arr.2026.103259

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clonal haematopoiesis of indeterminate potential and epigenetic age acceleration: Systematic review and meta-analysis.

Ageing research reviews - 1 Oct 2026

Simonson Matthew W, Mitra Sayan, Tay Jian Hua, Wang Weilan, Maier Andrea B

Abstract excerpt

Clonal haematopoiesis of indeterminate potential (CHIP) represents somatic mutations in haematopoietic stem cells that drive clonal expansion. Epigenetic age acceleration (EAA), estimated from DNA methylation (DNAm) clocks, may capture age-related changes in haematopoiesis. This systematic review and meta-analysis was conducted to synthesise evidence on associations between CHIP and EAA and explore shared...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Clonal Hematopoiesis
Share to DNA Methylation
Share to Epigenesis, Genetic

Source

Open in PubMed

Identifiers

PMID: 42463064
DOI: 10.1016/j.arr.2026.103259

Genes

DNMT3A
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNMT3A gene

Share to TET2 gene

Share to Hematopoiesis

Share to Mutation