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Article

Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease

2022-03-31

Abstract excerpt

<title>Abstract</title> <p>Age-related changes to the epigenome are well-documented, especially the pattern of genome-wide DNA methylation (DNAm) changes observed in blood. Clonal hematopoiesis of indeterminate potential (CHIP), characterized by the age-related acquisition and expansion of leukemogenic mutations in hematopoietic stem cells (HSCs), is associated with blood cancer and coronary artery disease (CAD)....

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Literature Corpus work
cbeff458-b3ee-5667-a29f-d014df6282d1
DOI
10.21203/rs.3.rs-1463822/v1
Open publication

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Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery diseaseDOI 10.21203/rs.3.rs-1463822/v1
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