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Article

History of Alcohol-Related Cancers and ADH1B/ALDH2 Genotypes in a Large Japanese Cohort of Male Patients With Alcohol Dependence.

Cancer medicine - 1 Jul 2026

Yokoyama Akira, Yokoyama Tetsuji

Abstract excerpt

BACKGROUND: Alcohol-dependent (AD) patients frequently present with a history of alcohol-related cancers, but the timing of cancer treatment relative to the onset of advanced alcohol use disorder and the role of ADH1B/ALDH2 genotypes remain unclear. METHODS: We reviewed cancer histories at the initial visit of 5214 Japanese male AD patients (mean age 53.3 [SD 11.9] years), all genotyped for ADH1B (rs1229984) and...

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Source

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Identifiers

PMID: 42415227
DOI: 10.1002/cam4.72092
PMCID: PMC13341646

Genes

ADH1B
ALDH2
GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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