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Trends in gastrectomy and ADH1B and ALDH2 genotypes in Japanese alcoholic men and their gene-gastrectomy, gene-gene and gene-age interactions for risk of alcoholism.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000

Yokoyama Akira, Yokoyama Tetsuji, Matsui Toshifumi, Mizukami Takeshi, Kimura Mitsuru, Matsushita Sachio, Higuchi Susumu, Maruyama Katsuya

Abstract excerpt

AIMS: The life-time drinking profiles of Japanese alcoholics have shown that gastrectomy increases susceptibility to alcoholism. We investigated the trends in gastrectomy and alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) genotypes and their interactions in alcoholics. METHODS: This survey was conducted on 4879 Japanese alcoholic men 40 years of age or older who underwent routine...

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Source

Identifiers

PMID: 23296215
DOI: 10.1093/alcalc/ags135

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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