Article
Genetic polymorphisms of ADH1B, ADH1C and ALDH2, alcohol consumption, and the risk of gastric cancer: the Japan Public Health Center-based prospective study.
Carcinogenesis - 1 Feb 2015
Hidaka Akihisa, Sasazuki Shizuka, Matsuo Keitaro, Ito Hidemi, Sawada Norie, Shimazu Taichi, Yamaji Taiki, Iwasaki Motoki, Inoue Manami, Tsugane Shoichiro
Abstract excerpt
The association between alcohol consumption, genetic polymorphisms of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) and gastric cancer risk is not completely understood. We investigated the association between ADH1B (rs1229984), ADH1C (rs698) and ALDH2 (rs671) polymorphisms, alcohol consumption and the risk of gastric cancer among Japanese subjects in a population-based, nested, case-control study...
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