Article
Tag single nucleotide polymorphisms of alcohol-metabolizing enzymes modify the risk of upper aerodigestive tract cancers: HapMap database analysis.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jul 2014
Chung C-S, Lee Y-C, Liou J-M, Wang C-P, Ko J-Y, Lee J-M, Wu M-S, Wang H-P
Abstract excerpt
Although alcohol is associated with higher upper aerodigestive tract (UADT) cancer risk, only a small fraction of alcoholics develop cancers. There is a lack of evidence proving the association of tag single nucleotide polymorphisms of alcohol-metabolizing enzymes with cancer risk. The aim of this study was to determine the association of these genetic polymorphisms with UADT cancer risk in a Chinese population....
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