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Article

Alcohol metabolism genes and risks of site-specific cancers in Chinese adults: An 11-year prospective study.

International journal of cancer - 15 May 2022

Im Pek Kei, Yang Ling, Kartsonaki Christiana, Chen Yiping, Guo Yu, Du Huaidong, Lin Kuang, Kerosi Rene, Hacker Alex, Liu Jingchao, Yu Canqing, Lv Jun, Walters Robin G, Li Liming, Chen Zhengming, Millwood Iona Y

Abstract excerpt

Two genetic variants that alter alcohol metabolism, ALDH2-rs671 and ADH1B-rs1229984, can modify oesophageal cancer risk associated with alcohol consumption in East Asians, but their associations with other cancers remain uncertain. ALDH2-rs671 G>A and ADH1B-rs1229984 G>A were genotyped in 150 722 adults, enrolled from 10 areas in China during 2004 to 2008. After 11 years' follow-up, 9339 individuals developed...

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Share to Alcohol Dehydrogenase
Share to Alcohol Drinking
Share to Aldehyde Dehydrogenase
Share to Aldehyde Dehydrogenase, Mitochondrial
Share to Asian People
Share to Esophageal Neoplasms
Share to Polymorphism, Single Nucleotide
Share to Risk Factors

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Identifiers

PMID: 35048370
DOI: 10.1002/ijc.33917
PMCID: PMC7612513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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