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Article

Ex vivo modulation of monocyte/macrophage phenotypes by all-trans retinoic acid in chemotherapy-induced peripheral neuropathy.

Molecular biology reports - 27 Jun 2026

Mohammad Talar Ahmad Merza

Abstract excerpt

BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating complication associated with chemotherapeutic agents such as paclitaxel, oxaliplatin, and cisplatin. Persistent inflammation and oxidative stress are key contributors to neuronal damage in CIPN. All-trans retinoic acid (ATRA) possesses antioxidant and immunomodulatory properties, suggesting potential therapeutic value in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42363989
DOI: 10.1007/s11033-026-12149-3

Genes

CD14
CD86

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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