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Article

Pathways related to PMA-differentiated THP1 human monocytic leukemia cells revealed by RNA-Seq

18 Nov 2015

Abstract excerpt

Previous analyses have reported that the human monocytic cell line THP1 can be differentiated into cells with macrophage-like characteristics by phorbol 12-myristate 13-acetate (PMA). However, little is known about the mechanism responsible for regulating this differentiation process. Here, we performed high-throughput RNA-Seq analysis to investigate the genes differently expressed in THP1 cells treated with and...

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PMID: 26582014
DOI: 10.1007/s11427-015-4967-4

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