Article
Pharmacological modulation of monocytes and macrophages.
Current opinion in pharmacology - 1 Aug 2014
Mantovani Alberto, Vecchi Annunciata, Allavena Paola
Abstract excerpt
Mononuclear phagocytes are major players in diverse pathological conditions which include chronic inflammatory diseases, infection, autoimmunity, atherosclerosis, metabolic disorders, and cancer. Plasticity is a fundamental property of cells of the monocyte-macrophage lineage and a variety of modulators profoundly affect monocytes and macrophages. Tumor-associated macrophages (TAMs) provide a paradigm for...
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