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Article

Xanthoplanine attenuates macrophage polarization towards M1 and inflammation response via disruption of CrkL-STAT5 complex.

Archives of biochemistry and biophysics - 15 Apr 2020

Shi Xiaofeng, Pan Shuang, Li Yongqi, Ma Wei, Wang Han, Xu Caiming, Li Lei

Abstract excerpt

Monocyte infiltration and macrophage polarization are widely considered as pivotal steps for the initiation and progression of atherosclerosis. Previous studies suggested that zanthoxylum piperitum had strong analgesic and anti-inflammatory effects. However, it remains unclear whether zanthoxylum piperitum inhibits inflammation via macrophage function. In the present study, we investigated the effects of...

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PMID: 32142888
DOI: 10.1016/j.abb.2020.108325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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