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Aging ADNP syndrome mice exhibit mutation/sex-dependent disruption of motor behavior and circadian rhythmicity.

Neurobiology of disease - 1 Sept 2026

Galushkin Artur, Giladi Eliezer, Gozes Illana

Abstract excerpt

Circadian disruption is an early and clinically relevant feature of Alzheimer's disease and related neurodegenerative conditions, yet the molecular determinants underlying its emergence remain incompletely understood. Activity-dependent neuroprotective protein (ADNP) is a key regulator of neurodevelopment and neuroprotection, with de novo mutations driving the neurodevelopmental ADNP syndrome tauopathy and with...

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PMID: 42361864
DOI: 10.1016/j.nbd.2026.107509

Genes

ADNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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