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Article

Alzheimer's disease-associated tau alters Drosophila circadian activity, sleep and clock neuron electrophysiology

14 Jun 2019

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia, which is associated with an enormous personal, social and economic burden worldwide. However, there are few current treatments with none of them targeting the underlying causes of the disease. Sleep and circadian rhythm defects are not only distressing symptoms of AD and other tauopathies and are a leading cause of care home admission but are also...

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PMID: 31207389
DOI: 10.1016/j.nbd.2019.104507

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