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Article

Spatially segregated B- and T-lymphoblasts in mixed-phenotype acute leukemia with BCR::ABL1.

Journal of hematopathology - 26 Jun 2026

Tam Ingrid S, Capo-Chichi José-Mario, Smith Adam C, Richard-Carpentier Guillaume, Xia Daniel

Abstract excerpt

BACKGROUND: Mixed phenotype acute leukemias (MPALs) account for approximately 2-5% of acute leukemias. PURPOSE: We report a case of MPAL with BCR::ABL1 demonstrating striking spatial segregation of B- and T-lymphoblasts involving the bone marrow and cervical lymph node, respectively. METHODS: Morphologic, immunophenotypic, and genetic characterization were performed. RESULTS: These studies identified two distinct...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42360373
DOI: 10.1007/s12308-026-00715-4

Genes

ABL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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