Article
Laboratory characterization of the pediatric B/T subtype of mixed-phenotype acute leukemia: Report of a case series.
American journal of clinical pathology - 1 Aug 2024
Demina Irina, Mikhailova Ekaterina, Zerkalenkova Elena, Semchenkova Alexandra, Roumiantseva Julia, Borkovskaya Alexandra, Matveev Evgeny, Abramov Dmitry, Konovalov Dmitry, Miakova Natalia, Ponomareva Natalia, Belkina Julia, Kondratchik Konstantin, Olshanskaya Yulia, Novichkova Galina, Karachunskiy Alexander, Popov Alexander
Abstract excerpt
OBJECTIVES: Mixed-phenotype acute leukemia (MPAL) is a rare disease associated with difficulties in the correct lineage assignment of leukemic cells. One of the least common subtypes within this category is characterized by the simultaneous presence of B- and T-lineage-defining antigens. Each case of suspected B/T MPAL should be considered in light of all available laboratory and clinical data to avoid...
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