Article
Clinical features and biological implications of acute mixed lineage (hybrid) leukemias.
The American journal of pediatric hematology/oncology - 1 Jan 1990
Altman A J
Abstract excerpt
The composite phenotype of a population of leukemic blast cells is derived through analysis of morphology, cytochemistry, cytogenetics, surface antigens, and gene structure. When analyzed in such a fashion, approximately 10-25% of childhood acute leukemias will show markers of more than one lineage; these may be coexpressed on individual cells (biphenotypic) or appear on two distinct blast populations (bilineal...
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