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Article

Epigenetic Control of Vascular Smooth Muscle Cell Function in Atherosclerosis: A Role for DNA Methylation.

DNA and cell biology - 1 Sept 2022

Chen Yanjun, Liang Lingli, Wu Chunyan, Cao Zitong, Xia Linzhen, Meng Jun, Wang Zuo

Abstract excerpt

Atherosclerosis is a complex vascular inflammatory disease in which multiple cell types are involved, including vascular smooth muscle cells (VSMCs). In response to vascular injury and inflammatory stimuli, VSMCs undergo a "phenotypic switching" characterized by extracellular matrix secretion, loss of contractility, and abnormal proliferation and migration, which play a key role in the progression of...

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Share to Atherosclerosis
Share to Cell Proliferation
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Phenotype

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Identifiers

PMID: 35900288
DOI: 10.1089/dna.2022.0278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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