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Article

Genetic diversity of Plasmodium falciparum helical interspersed subtelomeric (phistb) gene in Tanzania and neighboring countries.

Malaria journal - 24 Jun 2026

Mbwambo Ruth B, Pereus Dativa, Bakari Catherine, Moshi Ramadhan, Kisambale Angelina J, Madebe Rashid A, Misago Seth D, Mandara Celine I, Lyimo Beatus, Mbwambo Daniel, Aaron Sijenunu, Lusasi Abdallah, Lazaro Samwel, Juma Gerald, Kulohoma Benard W, Ishengoma Deus S

Abstract excerpt

BACKGROUND: Lysine-rich membrane associated Plasmodium helical interspersed subtelomeric gene (phistb) is a member of the phist family of genes which encodes exported proteins essential for the parasite's survival within infected red blood cells. Recent studies suggest the phistb gene as a promising malaria vaccine candidate, however, its genetic diversity remains understudied. This study assessed the genetic...

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Topics

Plasmodium falciparum
Genetic Variation
Tanzania
Protozoan Proteins
Uganda

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Kenya

Ethiopia

Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 42343434
DOI: 10.1186/s12936-026-06011-x
PMCID: PMC13555929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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