Article
Common and well-documented HLA alleles of German stem cell donors by haplotype frequency estimation.
HLA - 1 Oct 2018
Eberhard Hans-Peter, Schmidt Alexander H, Mytilineos Joannis, Fleischhauer Katharina, Müller Carlheinz R
Abstract excerpt
We present a catalog of common and well-documented (CWD) alleles of the German population for the six HLA loci A, B, C, DRB1, DQB1, and DPB1. This study is based on a sample of over 5 million volunteer adult hematopoietic stem cell donors from the 26 German donor centers. To establish the catalog, allele and haplotype frequencies were estimated with a validated implementation of the expectation-maximization...
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