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Article

Gene-predicted Causal Association of Immune Cell-mediated Plasma Metabolites with Acute Hepatitis B: A Mendelian Randomization Study.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Li Size, Fang Ting, Qi Wenying, Zheng Shihao, Wang Wei, Cheng Fan-E, Du HongBo, Zao Xiaobin, Li Xiaoke, Ye Yong'an

Abstract excerpt

INTRODUCTION: Acute Hepatitis B (AHB) remains a significant global health challenge, with complex interactions between metabolic and immune responses influencing disease progression. This study aimed to investigate the causal relationships between immune cell-mediated plasma metabolites and acute hepatitis B using Mendelian Randomization (MR) analysis. METHODS: A two-sample MR analysis was conducted using...

Read the complete abstract on PubMed

Topics

Humans
Mendelian Randomization Analysis
Hepatitis B
Genome-Wide Association Study
Acute Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Biomarkers

Risk Factors

Polymorphism, Single Nucleotide

Genetic Predisposition to Disease

Immunity, Cellular

Source

Identifiers

PMID: 42300297
DOI: 10.2174/0118715303431456260424063524

Genes

CD38
CD24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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