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Article

The role of immune cell phenotypes and metabolites in bipolar disorder risk: a Mendelian randomization-based mediation analysis.

European archives of psychiatry and clinical neuroscience - 1 Mar 2026

Zhou Xueying, Hu Ji

Abstract excerpt

BACKGROUND: Bipolar disorder (BD) is a multifactorial psychiatric disorder with contributions from genetic susceptibility and environmental exposures. Recent evidence suggests immune dysfunction and metabolic disturbances may contribute to BD, but the causal roles and mediation mechanisms remain ambiguous. METHODS: Two-sample MR analyses were conducted leveraging publicly accessible GWAS summary data to...

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PMID: 41191089
DOI: 10.1007/s00406-025-02120-x

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CD24
CD27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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