Article
Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Jun 2018
Hinks Anne, Marion Miranda C, Cobb Joanna, Comeau Mary E, Sudman Marc, Ainsworth Hannah C, Bowes John, Becker Mara L, Bohnsack John F, Haas Johannes-Peter, Lovell Daniel J, Mellins Elizabeth D, Nelson J Lee, Nordal Ellen, Punaro Marilynn, Reed Ann M, Rose Carlos D, Rosenberg Alan M, Rygg Marite, Smith Samantha L, Stevens Anne M, Videm Vibeke, Wallace Carol A, Wedderburn Lucy R, Yarwood Annie, Yeung Rae S M, Langefeld Carl D, Thompson Susan D, Thomson Wendy, Prahalad Sampath
Abstract excerpt
OBJECTIVE: Juvenile idiopathic arthritis (JIA) comprises 7 heterogeneous categories of chronic childhood arthritides. Approximately 5% of children with JIA have rheumatoid factor (RF)-positive arthritis, which phenotypically resembles adult rheumatoid arthritis (RA). Our objective was to compare and contrast the genetics of RF-positive polyarticular JIA with those of RA and selected other JIA categories, to more...
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