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Article

MIR1255A regulates pathways critical for brain development, risk genes for depression and neurodevelopmental disorders.

Translational psychiatry - 30 May 2026

Feng Yu, Wigg Karen G, Barr Cathy L

Abstract excerpt

Multiple lines of evidence implicate microRNAs (miRNAs) in major depressive disorder (MDD), including the location of miRNAs genes (MIRs) within genomic regions identified by genome wide association studies (GWAS). To investigate the role of MIRs in the genetic risk for MDD, we identified all associated single nucleotide polymorphism (SNPs) that were expression quantitative loci (eQTLs) for MIRs in brain tissues....

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Identifiers

PMID: 42218122
DOI: 10.1038/s41398-026-04126-y
PMCID: PMC13434240

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