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Genetic architecture of miRNA expression in human brain and its contribution to brain disorders

2026-01-16

Abstract excerpt

MicroRNAs (miRNAs) regulate nearly all protein-coding genes and play critical roles in gene regulation, yet the mechanisms governing miRNA regulation remain poorly understood. Here, we examined the genetic architecture of miRNA expression in 995 human brain tissues spanning four regions and two ancestries (African and European) from neurotypical controls and individuals with three psychiatric disorders (schizophre...

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Literature Corpus work
90ac434b-86e7-59bc-86c8-0bb1543b37dc
DOI
10.64898/2026.01.15.699788
Open publication

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