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Article

Genetic variants in miRNAs differentially expressed during brain development and their relevance to psychiatric disorders susceptibility.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jul 2021

Brum Clarice Brinck, Paixão-Côrtes Vanessa Rodrigues, Carvalho Andressa Marques, Martins-Silva Thais, Carpena Marina Xavier, Ulguim Kauana Ferreira, Luquez Karen Yumaira Sánchez, Salatino-Oliveira Angélica, Tovo-Rodrigues Luciana

Abstract excerpt

OBJECTIVES: MicroRNAs (miRNAs) play an important regulatory role in the expression of genes involved in brain functions during development. Genetic variants in miRNA genes may impact their regulatory function and lead to psychiatric disorders. To evaluate the role of genetic variants in genes of miRNAs differentially expressed during neurodevelopment on autism spectrum disorder (ASD), attention...

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PMID: 33040684
DOI: 10.1080/15622975.2020.1834618

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