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Article

Regulatory mechanisms of major depressive disorder risk variants.

Molecular psychiatry - 1 Sept 2020

Li Shiwu, Li Yifan, Li Xiaoyan, Liu Jiewei, Huo Yongxia, Wang Junyang, Liu Zhongchun, Li Ming, Luo Xiong-Jian

Abstract excerpt

Major depressive disorder (MDD) is one of the most prevalent psychiatric disorders and a leading cause of disability worldwide. Though recent genome-wide association studies (GWAS) have identified multiple risk variants for MDD, how these variants confer MDD risk remains largely unknown. Here we systematically characterize the regulatory mechanism of MDD risk variants using a functional genomics approach. By...

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PMID: 32214206
DOI: 10.1038/s41380-020-0715-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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