Article
Trimethoprim/sulfamethoxazole-triggered drug-induced hypersensitivity syndrome in an HLA B*13:01-positive kidney transplant recipient: a case report with implications for HLA-severe cutaneous adverse reaction associations in transplant care.
CEN case reports - 30 May 2026
Tomizawa Mitsuru, Hori Shunta, Inoue Kuniaki, Yoneda Tatsuo, Akioka Nobuya, Nishimura Yuki, Asada Hideo, Nakai Yasushi, Miyake Makito, Fujimoto Kiyohide
Abstract excerpt
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe cutaneous adverse reaction (SCAR) with a reported mortality rate of approximately 2-10%. DIHS/DRESS typically develops 2-8 weeks after exposure to an offending drug. An important focus of contemporary SCAR research is the growing evidence that specific human leukocyte antigen (HLA) alleles confer...
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