Article
HLA-B*13:01 is associated with salazosulfapyridine-induced drug rash with eosinophilia and systemic symptoms in Chinese Han population.
Pharmacogenomics - 1 Aug 2014
Yang Fanping, Gu Bo, Zhang Lirong, Xuan Jiekun, Luo Heng, Zhou Peng, Zhu Qinyuan, Yan Sijia, Chen Sheng-an, Cao Zhihao, Xu Jinhua, Xing Qinghe, Luo Xiaoqun
Abstract excerpt
AIM: Salazosulfapyridine (SASP) frequently causes several adverse reactions, such as drug rash with eosinophilia and systemic symptoms (DRESS). This study aims to assess whether there is an association between SASP-induced DRESS and HLA-A, -B and -C alleles in the Chinese Han population. SUBJECTS & METHODS: We performed an association study of six subjects with SASP-induced DRESS, 30 SASP-tolerant patients and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
