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Article

Severe Delayed Cutaneous and Systemic Reactions to Drugs: A Global Perspective on the Science and Art of Current Practice.

The journal of allergy and clinical immunology. In practice - 1 Jan 2000

Peter Jonathan Grant, Lehloenya Rannakoe, Dlamini Sipho, Risma Kimberly, White Katie D, Konvinse Katherine C, Phillips Elizabeth J

Abstract excerpt

Most immune-mediated adverse drug reactions (IM-ADRs) involve the skin, and many have additional systemic features. Severe cutaneous adverse drug reactions (SCARs) are an uncommon, potentially life-threatening, and challenging subgroup of IM-ADRs with diverse clinical phenotypes, mechanisms, and offending drugs. T-cell-mediated immunopathology is central to these severe delayed reactions, but effector cells and...

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Source

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Identifiers

PMID: 28483310
DOI: 10.1016/j.jaip.2017.01.025
PMCID: PMC5424615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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