Modulation of CREB signaling contributes to anxiety-like phenotypes in a kindling model of adult zebrafish.

Abstract excerpt

Epilepsy is a chronic neurological condition that is often accompanied by psychiatric comorbidities, including anxiety and social dysfunction. Several animal models of epilepsy exist but they are costly, laborious, and ethically constrained. In this regard, zebrafish (Danio rerio) offer a promising alternative animal model. However, most epilepsy studies have focused on acute seizure models, and long-term...

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