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Article

Genome-Wide Association Study of Psoriasis, Psoriatic Arthritis, Anti-TNF-α Response, and Polygenic Risk Score in a Russian Cohort.

International journal of molecular sciences - 15 May 2026

Karamova Arfenya E, Buianova Anastasiia A, Vorontsova Anastasiia A, Kubanov Alexey A

Abstract excerpt

Psoriasis is an immune-mediated inflammatory disease with a genetic component, characterized by dysregulation of cytokine signaling and activation of T lymphocytes. This study investigated genetic variants associated with psoriasis, psoriatic arthritis (PsA), and response to tumor necrosis factor alpha (TNF-α) inhibitors (adalimumab, infliximab, and etanercept) in a Russian cohort. A genome-wide association study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42196396
DOI: 10.3390/ijms27104422
PMCID: PMC13207559

Genes

TNF
FBLIM1
IL18R1
IL18RAP
PLCL2
RCL1
ZC3H8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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