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A pilot shotgun proteomic profiling of peripheral blood mononuclear cells in patients with different MRI phenotypes of cerebral small vessel disease.

Biomeditsinskaia khimiia - 1 May 2026

Geints A A, Shlapakova P S, Dobrynina L A, Kremneva E I, Khriapova E V, Zgoda V G, Tikhonova O V

Abstract excerpt

Age-related cerebral microangiopathy (CMA) also known as cerebral small vessel disease (CSVD), is a leading cause of cognitive impairment and stroke. Difficulties in studying CSVD are associated with limitations in visualizing small vessels and diagnostics based on MRI signs of brain damage (white matter hyperintensity, lacunae, microbleeds, etc.). Our previous assessment of each CSVD MRI feature using a...

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PMID: 42183763
DOI: 10.18097/PBMCR1643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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