In-depth cerebrovascular lipidomics profiling for discovering novel biomarkers and mechanisms in moyamoya and intracranial atherosclerotic disease

Abstract excerpt

BACKGROUND: Despite considerable research efforts, the precise etiology and underlying pathways contributing to moyamoya disease (MMD) remain poorly understood. Moreover, the overlapping vascular pathologies shared between MMD and intracranial atherosclerotic disease (ICAD) pose challenges in clinical differentiation, even with gold-standard cerebral angiography. An in-depth exploration of lipidomic alterations...

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