Article

Proteome Profiling of Serum Reveals Pathological Mechanisms and Biomarker Candidates for Cerebral Small Vessel Disease

2024-12-18

Abstract excerpt

<title>Abstract</title> <p>Background Cerebral small vessel disease (CSVD) is a global brain disorder that is characterized by a series of clinical, neuroimaging, and neuropathological manifestations. However, the molecular pathophysiological mechanisms of CSVD have not been thoroughly investigated. Liquid chromatography-tandem mass spectrometry-based proteomics has broad application prospects in biomedicine. It...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d144e29d-dc26-5c8e-9aa4-fdc2d473be12
DOI: 10.21203/rs.3.rs-5439901/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Proteome Profiling of Serum Reveals Pathological Mechanisms and Biomarker Candidates for Cerebral Small Vessel DiseaseDOI 10.21203/rs.3.rs-5439901/v1Read

A pilot shotgun proteomic profiling of peripheral blood mononuclear cells in patients with different MRI phenotypes of cerebral small vessel disease.Semantic proximity Read

Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel diseaseSemantic proximity Read

Predictive modeling of angiotensin-converting enzyme and its gene-polymorphisms in the occurrence of cerebral small-vessel diseaseSemantic proximity Read

Clinical Phenotypes Associated With Cerebral Small Vessel Disease: An Overview of Systematic Reviews.Semantic proximity Read

Potential biomarkers of Alzheimer’s disease and cerebral small vessel diseaseSemantic proximity Read

Identification of differentially expressed exosome proteins in serum as potential biomarkers for cognitive impairments in cerebral small vessel diseaseSemantic proximity Read

Serum Olink Proteomics-Based Identification of Protein Biomarkers Associated with the Immune Response in Ischemic StrokeSemantic proximity Read

Clinical Phenotypes Associated With Cerebral Small Vessel Disease: A Study of 45,013 UK Biobank Participants.Semantic proximity Read

[Hereditary cerebral small-vessel disease].Semantic proximity Read

A foundation model for mapping the phenomic and genetic landscape of cerebral small vessel disease biomarkersSemantic proximity Read

Rare Sequence Variation Underlying Suspected Familial Cerebral Small-Vessel Disease.Semantic proximity Read

Data-Independent Acquisition-Based Serum Proteomic Profiling of Adult Moyamoya Disease Patients Reveals the Potential Pathogenesis of Vascular ChangesSemantic proximity Read