Genetic and Molecular Interconnections Between Chronic Obstructive Pulmonary Disease and Osteoporosis: Insights from Single-Cell and Mendelian Randomization Analyses.

Abstract excerpt

Background: Chronic obstructive pulmonary disease (COPD) and osteoporosis are common comorbid conditions, both of which impose a significant health burden. This research employs single-cell data and Mendelian randomization analysis to pinpoint genes associated with both conditions and investigate their possible mechanistic links. Methods: Single-cell datasets pertaining to chronic obstructive pulmonary disease...

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