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Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

1 Jul 2025

Abstract excerpt

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia and insulin resistance, Migraine is a common chronic neurological disease caused by increased excitability of the central nervous system, both exerting substantial health burdens. However, the shared genetic basis and underlying molecular mechanisms remain largely unexplored. This study integrates single-cell data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40596821
DOI: 10.1186/s10194-025-02090-4

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