Article
Potential marker genes for chronic obstructive pulmonary disease revealed based on single-cell sequencing and Mendelian randomization analysis.
Aging - 23 May 2024
Sun Gang, Zhou Yun, Han Xiaoxiao, Che Xiangqian, Yu Shuo, Song Di, Ma Feifei, Huang Lewei
Abstract excerpt
BACKGROUND: Progress is being made in the prevention and treatment of chronic obstructive pulmonary disease (COPD), but it is still unsatisfactory. With the development of genetic technology, validated genetic information can better explain COPD. OBJECTIVE: The study utilized scRNA-seq and Mendelian randomization analysis of eQTLs to identify crucial genes and potential mechanistic pathways underlying COPD...
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