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Article

ER Stress-Related Biomarkers in Chronic Obstructive Pulmonary Disease: A Comprehensive Transcriptome, Mendelian Randomization, and Machine-Learning Analysis.

International journal of chronic obstructive pulmonary disease - 1 Jan 2025

Li Jiajia, Li Guofeng, Liu Junnan, Li Lijie, Zhou Huiling, Fei Xinru, Wen Yuhua, Zhao Dongkai

Abstract excerpt

Background: Chronic obstructive pulmonary disease (COPD) is a common respiratory disease; however, measures for preventing COPD and delaying disease progression are limited. Therefore, identifying genetic variations and novel biomarkers related to COPD incidence and progression is crucial for improving clinical outcomes. Here, we investigated the potential of the endoplasmic reticulum stress-related gene DNAJB1...

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Topics

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Share to Databases, Genetic
Share to Endoplasmic Reticulum Stress

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to HSP40 Heat-Shock Proteins

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Share to Pulmonary Disease, Chronic Obstructive

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Source

Open in PubMed Open full text

Identifiers

PMID: 41328289
DOI: 10.2147/COPD.S548160
PMCID: PMC12665228

Genes

DNAJB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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