Article
Reclassification of TCGA Diffuse Glioma Profiles Linked to Transcriptomic, Epigenetic, Genomic and Clinical Data, According to the 2021 WHO CNS Tumor Classification.
International journal of molecular sciences - 21 Dec 2022
Zakharova Galina, Efimov Victor, Raevskiy Mikhail, Rumiantsev Pavel, Gudkov Alexander, Belogurova-Ovchinnikova Oksana, Sorokin Maksim, Buzdin Anton
Abstract excerpt
In 2021, the fifth edition of the WHO classification of tumors of the central nervous system (WHO CNS5) was published. Molecular features of tumors were directly incorporated into the diagnostic decision tree, thus affecting both the typing and staging of the tumor. It has changed the traditional approach, based solely on histopathological classification. The Cancer Genome Atlas project (TCGA) is one of the main...
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