Article
Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing.
Pathology oncology research : POR - 1 Jan 2023
Wang Qiang, Liang Qiujin, Wei Wuting, Niu Wenhao, Liang Chong, Wang Xiaoliang, Wang Xiaoxuan, Pan Hao
Abstract excerpt
Purpose: The driver mutations of gliomas have been identified in cerebrospinal fluid (CSF). Here we compared the concordance between CSF and tumor tissue for integrated diagnosis in gliomas using next-generation sequencing (NGS) to evaluate the feasibility of CSF detection in gliomas. Patients and methods: 27 paired CSF/tumor tissues of glioma patients were sequenced by a customized gene panel based on NGS. All...
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