Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid.

Journal of neuro-oncology - 1 Mar 2021

Fujioka Yutaka, Hata Nobuhiro, Akagi Yojiro, Kuga Daisuke, Hatae Ryusuke, Sangatsuda Yuhei, Michiwaki Yuhei, Amemiya Takeo, Takigawa Kosuke, Funakoshi Yusuke, Sako Aki, Iwaki Toru, Iihara Koji, Mizoguchi Masahiro

Abstract excerpt

PURPOSE: Conventional genetic analyzers require surgically obtained tumor tissues to confirm the molecular diagnosis of diffuse glioma. Recent technical breakthroughs have enabled increased utilization of cell-free tumor DNA (ctDNA) in body fluids as a reliable resource for molecular diagnosis in various cancers. Here, we tested the application of a chip-based digital PCR system for the less invasive diagnosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Circulating Tumor DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Histones

Share to Isocitrate Dehydrogenase

Share to Liquid Biopsy

Share to Pathology, Molecular

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 33417137
DOI: 10.1007/s11060-020-03682-7
PMCID: PMC7910241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid.PMID 33417137Read ↗

Molecular Diagnosis of Diffuse Gliomas through Sequencing of Cell-Free Circulating Tumor DNA from Cerebrospinal Fluid.Semantic proximity Read ↗

CSF ctDNA analysis guides molecular reclassification of diffuse glioma patients.Semantic proximity Read ↗

Clinical utility of plasma cell-free DNA (cfDNA) in diffuse gliomas for the detection of IDH1 R132H mutation.Semantic proximity Read ↗

A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic ApplicationsSemantic proximity Read ↗

Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas.Semantic proximity Read ↗

Molecular diagnostic testing of diffuse gliomas in the real-life setting: A practical approach.Semantic proximity Read ↗

Applications of cerebrospinal fluid circulating tumor DNA in the diagnosis of gliomas.Semantic proximity Read ↗

Clinical implications of molecular analysis in diffuse glioma stratification.Semantic proximity Read ↗

The clinical use of IDH1 and IDH2 mutations in gliomasSemantic proximity Read ↗

Clinical Application of Comprehensive Genomic Profiling Tests for Diffuse GliomasSemantic proximity Read ↗

Rapid intraoperative genetic analysis of adult-type diffuse gliomas using a microfluidic real-time polymerase chain reaction device.Semantic proximity Read ↗

Cerebrospinal fluid-derived genomic alterations tracking gliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.