Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Residual genetic connectivity beyond shared liability in 14 psychiatric disorders.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jul 2026

Chang Yu, Hsieh Ming-Hong, Ju Po-Chung, Chang Cheng-Chen

Abstract excerpt

OBJECTIVES: Transdiagnostic genetic factor models organise shared liability across psychiatric disorders, but they may leave systematic pairwise genetic overlap unexplained after accounting for shared liability. METHODS: Using publicly available Psychiatric Genomics Consortium cross-disorder published genetic correlations, we computed edge-level residual genetic correlations (observed minus model-implied) for all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Mental Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Source

Identifiers

PMID: 42160754
DOI: 10.1080/15622975.2026.2671795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Residual genetic connectivity beyond shared liability in 14 psychiatric disorders.PMID 42160754Read ↗

Mapping unexplained genetic correlations across 14 psychiatric disordersSemantic proximity Read ↗

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders.Semantic proximity Read ↗

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disordersSemantic proximity Read ↗

Shared genetic architecture across psychiatric disorders.Semantic proximity Read ↗

Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation.Semantic proximity Read ↗

Genetic network structure of 13 psychiatric disorders in the general population.Semantic proximity Read ↗

Genetic and phenotypic similarity across major psychiatric disorders: a systematic review and quantitative assessment.Semantic proximity Read ↗

Shared Genetic Liability across Systems of Psychiatric and Physical Illness.Semantic proximity Read ↗

Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis.Semantic proximity Read ↗

Integrating HiTOP and RDoC Frameworks Part I: Genetic Architecture of Externalizing and Internalizing PsychopathologySemantic proximity Read ↗

Testing structural models of psychopathology at the genomic levelSemantic proximity Read ↗

A structural brain network of genetic vulnerability to psychiatric illness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.