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Isolation and characterization of Saccharomyces cerevisiae mutants with ornithine accumulation for value-added craft beer brewing.

Journal of industrial microbiology & biotechnology - 8 Jan 2026

Nishimura Akira, Isogai Shota, Yamada Koya, Tanahashi Ryoya, Takagi Hiroshi

Abstract excerpt

Ornithine is a nonproteinogenic amino acid with various health benefits, making it a promising target for functional food development. In this study, we developed the yeast Saccharomyces cerevisiae strains with elevated intracellular ornithine and identified the genetic mutation responsible for this trait. An ornithine-rich mutant was successfully isolated by chemical mutagenesis and selection for resistance to...

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PMID: 42159295
DOI: 10.1093/jimb/kuag013
PMCID: PMC13261765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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