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Modification of the second PEP4-allele facilitates an industrial Saccharomyces cerevisiae to tolerate tartaric acid stress.

Research in microbiology - 1 Jan 2000

Zhang Hongbo, Yang Xiaomei, Shen Chi, Sun Jianqiu, Lu Yuhang, Hu Wanting, Yao Hongfei, Zhao Wenhao

Abstract excerpt

The practical significance of constructing robust industrial production strains against organic acid stress lies not only in improving fermentation efficiency but also in reducing manufacturing costs. In a previous study, we constructed an industrial Saccharomyces cerevisiae strain by modifying another PEP4-allele of a mutant that already had one PEP4-allele disrupted. This modification enhanced cellular...

Topics

Saccharomyces cerevisiae
Alleles
Saccharomyces cerevisiae Proteins
Citric Acid
Fermentation
Aspartic Acid Endopeptidases

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37517628
DOI: 10.1016/j.resmic.2023.104109

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