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Article

Metabolic engineering of arginine permeases to reduce the formation of urea in Saccharomyces cerevisiae.

World journal of microbiology & biotechnology - 13 Mar 2018

Zhang Peng, Hu Xing

Abstract excerpt

Urea is an important precursor of the harmful carcinogenic product ethyl carbamate in fermented wines. To decipher more fully the contributions of three arginine permeases, Can1p, Gap1p and Alp1p in urea formation, various engineered strains were examined for their ability to form urea. This included seven mutants with different combinations of permease deficiency and grown in both simple and more complex media,...

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PMID: 29536194
DOI: 10.1007/s11274-018-2430-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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