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Article

Allele frequencies of pharmacogenetic biomarkers and genomic ancestry in a sample of the Cuban population.

Drug metabolism and personalized therapy - 1 Jun 2026

Roblejo-Balbuena Hilda, Zuñiga-Rosales Yaima, Martínez-Téllez Goitybell, Alemañy Díaz-Perera Claudia, Monzón-Benítez Giselle, Bybjerg-Grauholm Jonas, Mors Ole, Marcheco-Teruel Beatriz

Abstract excerpt

OBJECTIVES: A growing set of drugs includes a pharmacogenetic biomarker as a requirement before prescription. This study aims to determine the frequency of allelic variants with functional repercussions in clinically relevant pharmacogenes and its relation with genomic ancestry in Cuban individuals. METHODS: 10 single nucleotide variants (SNVs) across eight genes, included in the list of genetic variants required...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42154610
DOI: 10.1515/dmpt-2025-0038

Genes

CYP2C9
SLCO1B1
CYP3A5
CYP4F2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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