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Article

Clinical genetic variation across Hispanic populations in the Mexican Biobank.

Nature medicine - 1 Feb 2026

Barberena-Jonas Carmina, Medina-Muñoz Santiago G, Cedillo-Castelán Viankail, Sepúlveda-Morales Tania, Gonzaga-Jáuregui Claudia, García-García Lourdes, Ioannidis Alexander G, Moreno-Estrada Andrés

Abstract excerpt

Genetic testing for specific alleles is often recommended based on an individual's ancestry. However, the frequency of pathogenic and pharmacogenomic alleles across different Hispanic groups has not been well characterized, and existing guidelines often fail to recognize the geographic and ancestral diversity within these populations. Here analyzing data from 6,011 individuals from the nationwide Mexican Biobank,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41566040
DOI: 10.1038/s41591-025-04100-z
PMCID: PMC12920135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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